Zolpimist is a prescription medicine used for treating insomnia. It is specifically approved for the short-term treatment of insomnia in people with difficulty falling asleep (rather than people who have trouble staying asleep). The medication comes in the form of an oral spray that is sprayed directly into the mouth immediately before bedtime. Potential side effects include drowsiness, dizziness, and headaches.

What Is Zolpimist?

Zolpimist® (zolpidem oral spray) is a prescription medication approved for the short-term treatment of insomnia in people with difficulty falling asleep (as opposed to difficulty staying asleep). It contains the same active ingredient as Ambien® and Ambien CR®, except it comes in the form of a fast-acting oral spray, instead of a tablet.
Like many other sleep medications, it is a controlled substance and may be abused.
(Click Zolpimist Uses for more information, including possible off-label uses.)

Who Makes This Medication?

Zolpimist is made by Rechon Life Sciences AB and is marketed by ECR Pharmaceuticals.

How Does Zolpimist Work?

Zolpimist is part of a class of medications called sedative/hypnotics, which are known more commonly as sleep medicines. It is thought that Zolpimist works by binding to certain receptors in the brain known as benzodiazepine receptors. It should be noted that Zolpimist is not a benzodiazepine drug and is not chemically related to benzodiazepines, even though it binds to the same receptors.

Zolpimist Effects

Studies have shown that Zolpimist helps people fall asleep faster, stay asleep longer, and wake up less frequently, compared to a placebo spray (with no active ingredients). Studies have also shown that Zolpimist (at the recommended dosage) is unlikely to cause a "hangover" effect the next day and is unlikely to cause rebound insomnia (a worsening of insomnia once the medication is stopped).
Studies of Zolpimist have been relatively short (a few weeks in duration), and it is not clear if this medication is effective when used for more than 35 days.

Zolpimist Medication Information

Referring Pages:
Terms of Use
Advertise with Us
Contact Us
About eMedTV
Privacy Policy
Copyright © 2006-2020 Clinaero, Inc.
eMedTV serves only as an informational resource. This site does not dispense medical advice or advice of any kind. Site users seeking medical advice about their specific situation should consult with their own physician. Click Terms of Use for more information.