Zolpimist Warnings and Precautions

Before you start using Zolpimist, precautions and warnings for the drug should be reviewed with your healthcare provider. It is important to know that Zolpimist must be used with caution in people with sleep apnea or other breathing problems, as it could worsen these conditions. The medicine may also cause or worsen depression, so tell your healthcare provider if you have depression before starting Zolpimist.

What Should I Tell My Healthcare Provider Before Taking Zolpimist?

You should talk with your healthcare provider prior to taking Zolpimist® (zolpidem oral spray) if you have:
Also, let your healthcare provider know if you are:
  • Pregnant or thinking of becoming pregnant
  • Breastfeeding.
Make sure to tell your healthcare provider about any other medications you are taking, including prescription and non-prescription medicines, vitamins, and herbal supplements.

Specific Precautions and Warnings for Zolpimist

Some things to be aware of prior to taking Zolpimist include the following:
  • In January 2013, the U.S. Food and Drug Administration lowered the recommended dosage for Zolpimist for women and suggested that a lower dosage be considered for men as well. This change was made because the lower dosage is less likely to cause morning drowsiness, which can interfere with your ability to do anything that requires alertness, such as driving (see Zolpimist Dosage for more information).
  • You should only take Zolpimist if you have the chance for a full seven or eight hours of sleep. Never drive or operate heavy machinery after you have taken a dose of Zolpimist, even if you do not feel drowsy yet.
  • If you drink alcohol, let your healthcare provider know prior to starting Zolpimist. In general, people should not use alcohol when taking this medication because it can increase the risks of developing Zolpimist side effects.
  • If you notice any changes in your behavior (such as anything unusual or disturbing) while taking Zolpimist or other sleep medicines, notify your healthcare provider immediately. Bizarre thoughts or behavior have been reported with Zolpimist.
  • Be aware that you may get out of bed while not fully awake and do things that you may not remember, such as sleep-walking or sleep-eating. If this happens, your healthcare provider will probably recommend that you stop taking Zolpimist.
  • Zolpimist can cause severe allergic reactions. If you have an allergic reaction to this medication, you should never take it again.
  • Zolpimist should be used with caution in people with sleep apnea or other breathing problems, as it could make such problems worse.
  • Zolpimist has been reported to cause or worsen depression. Let your healthcare provider know if you think you may be depressed (or if your depression is worsening).
  • Liver disease may affect the way your body handles Zolpimist. You may need a lower Zolpimist dosage.
  • Zolpimist can potentially interact with several other medications (see Zolpimist Drug Interactions).
  • Zolpimist is considered a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are not known (see Zolpimist and Pregnancy).
  • Zolpimist passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Zolpimist and Breastfeeding).

Zolpimist Medication Information

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