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Valerian Drug Interactions
There are several medications that may interact with valerian. For example, drug interactions may occur if the supplement is taken with antidepressants, alcohol, antipsychotic medications, narcotics, and other sleep medications, to name a few. Some of these interactions can increase the risk of developing serious side effects, such as drowsiness, confusion, memory loss, and difficulty breathing.
Even though valerian is a natural product, it can potentially interact with several medicines. Some of the medicines that may lead to drug interactions with this product include:
- Alcohol
- Antidepressants
- Antipsychotic medications, such as:
- Aripiprazole (Abilify®)
- Asenapine (Saphris®)
- Chlorpromazine (Thorazine®)
- Clozapine (Clozaril®, FazaClo®)
- Fluphenazine (Prolixin®)
- Haloperidol (Haldol®)
- Iloperidone (Fanapt®)
- Loxapine (Adasuve™, Loxitane®)
- Lurasidone (Latuda®)
- Molindone (Moban®)
- Olanzapine (Zyprexa®, Symbyax®)
- Paliperidone (Invega®)
- Perphenazine (Trilafon®)
- Pimozide (Orap®)
- Prochlorperazine (Compazine®, Compro®)
- Quetiapine (Seroquel®)
- Risperidone (Risperdal®)
- Thioridazine (Mellaril®)
- Thiothixene (Navane®)
- Trifluoperazine (Stelazine®)
- Ziprasidone (Geodon®)
- Barbiturates, such as:
- Amobarbital (Amytal®)
- Butalbital (Fioricet®, Fiorinal®)
- Pentobarbital (Nembutal®)
- Phenobarbital (Luminal®)
- Secobarbital (Seconal®)
- Benzodiazepines, such as:
- Narcotics or opiates, such as:
- Other sleep medications.
Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD