Sonata and Depression

For those who are taking Sonata, depression is one of the more common side effects seen with the drug. Since depression is such a common condition in the general population, however, it is difficult to determine whether it is actually caused by Sonata or other factors. If you are taking Sonata and depression symptoms develop, be sure to notify your healthcare provider immediately.

Is Depression a Sonata Side Effect?

There are several possible side effects for people taking Sonata® (zaleplon). Depression does appear to be one of the more common side effects reported in clinical studies.
 

Understanding Clinical Studies

Before medicines are approved, they must go through several clinical studies in which thousands of people are given a particular medicine and compared to a group of people not given the medicine. In these studies, side effects are always documented. This way, it is possible to see what side effects occur, how often they appear, and how they compare to the group not taking the medicine. Side effects are then usually separated into those that occur in more than 1 percent of people and those that occur in less than 1 percent of people.
 
For people taking Sonata, depression was reported as a frequent side effect, occurring in more than 1 percent of people. No specific information on the exact percentage of people who developed depression while taking Sonata in these clinical studies is available.
 
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