Rozerem Interactions

When alcohol and other drugs are taken at the same time with Rozerem, interactions can potentially occur. These drug interactions can significantly increase the levels of Rozerem in the blood, which also increases the risk of developing side effects. Medications that can lead to Rozerem interactions include: fluvoxamine, ketoconazole, and rifampin, among others.

 

Rozerem Drug Interactions: An Overview

Rozerem® (ramelteon) can potentially interact with many drugs. Some of the drugs that may lead to Rozerem interactions include:
 
  • Alcohol
  • Fluconazole (Diflucan®)
  • Ketoconazole (Nizoral®)
  • Fluvoxamine (Luvox®)
  • Rifampin (Rifadin®).
     

Rozerem Interactions Explained

 
Alcohol
When alcohol and Rozerem are taken at the same time, Rozerem may increase the effects of the alcohol. It is, therefore, recommended that you do not drink alcohol when taking Rozerem.
 
Fluconazole (Diflucan)
Taking Rozerem with fluconazole can increase the level of Rozerem in the blood, increasing your chance of developing side effects. Talk to your healthcare provider before taking these two medications together.
 
Ketoconazole (Nizoral)
Taking Rozerem with ketoconazole can increase the level of Rozerem in the blood, increasing your chance of developing side effects. Talk to your healthcare provider before taking these two medications together.
 
Fluvoxamine (Luvox)
Taking Rozerem with fluvoxamine can cause extremely high levels of Rozerem in the blood, increasing your risk of side effects. Do not take these two medications together.
(Rozerem Interactions Continued: Page 2)
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Written by/reviewed by: Kristi Monson, PharmD; Arthur Schoenstadt, MD
Last reviewed by: Kristi Monson, PharmD;