Lunesta Drug Interactions

There are many drugs that can lead to negative interactions when taken together with Lunesta. Drug interactions may significantly increase the level of Lunesta in your blood, which increases your risk of developing side effects. Lunesta drug interactions may occur if the sleeping medicine is taken with alcohol, certain anticonvulsants, protease inhibitors, or rifamycin antibiotics, among other drugs.

• Alcohol
   
• Certain antibiotics or antifungals, including:

o Clarithromycin (Biaxin^®)

o Isoniazid (Nydrazid^®)

o Itraconazole (Sporanox^®)

o Ketoconazole (Nizoral^®)

o Miconazole

o Telithromycin (Ketek^®)

• Certain anticonvulsants, including:

o Carbamazepine (Tegretol^®, Carbatrol^®, Epitol^®)

o Fosphenytoin (Cerebyx^®)

o Oxcarbazepine (Trileptal^®)

o Phenobarbital (Luminal^®)

o Pentobarbital (Nembutal^®)

o Phenytoin (Dilantin^®, Phenytek^®)

o Primidone (Mysoline^®)

• Delavirdine (Rescriptor^®)
   
• Diclofenac (Cataflam^®, Voltaren^®)
   
• Imatinib (Gleevec^®)
   
• Nefazodone (Serzone^®)
   
• Nevirapine (Viramune^®)
   
• Nicardipine (Cardene^®)
   
• Olanzapine (Zyprexa^®, Symbyax^®)
   
• Protease inhibitors, such as:

o Amprenavir (Agenerase^®)

o Atazanavir (Reyataz^®)

o Fosamprenavir (Lexiva^®)

o Indinavir (Crixivan^®)

o Nelfinavir (Viracept^®)

o Ritonavir (Norvir^®)

• Rifamycin antibiotics, including rifabutin (Mycobutin^®), rifampin (Rifadin^®), and rifapentine (Priftin^®).