Intermezzo Warnings and Precautions
It is important for your healthcare provider to know if you have depression or any type of respiratory disease before starting treatment with Intermezzo. Other safety precautions include warnings of potentially dangerous allergic reactions or drug interactions. Also, Intermezzo may not be safe for use in women who are pregnant or breastfeeding.
You should talk with your healthcare provider prior to taking Intermezzo® (zolpidem sublingual tablet) if you have:
- Sleep apnea or another type of respiratory disease, such as emphysema or chronic obstructive pulmonary disease (COPD)
- Liver disease or liver failure, including cirrhosis
- Any allergies, including to foods, dyes, or preservatives.
Also, let your healthcare provider know if you are:
- Pregnant or thinking of becoming pregnant
In addition, tell your healthcare provider about all other medications you are taking, including prescription and nonprescription medicines, vitamins, and herbal supplements.
Some warnings and precautions to be aware of prior to using this medicine include the following:
- You should only take Intermezzo if you have the chance for four more hours of additional sleep. Never drive or operate heavy machinery shortly after you have taken a dose of Intermezzo, even if you do not feel drowsy. If for some reason you take Intermezzo and must wake up sooner than four hours later, be aware that you may be quite drowsy and unable to drive safely.
- If you drink alcohol, let your healthcare provider know prior to starting Intermezzo. In general, people should not use alcohol when taking this medication, as it can increase the risks for developing Intermezzo side effects.
- If you notice any changes in your behavior, such as anything unusual or disturbing, while taking Intermezzo or other sleep medicines, notify your healthcare provider immediately. Bizarre thoughts or behavior have been reported with Intermezzo.
- Be aware that you may get out of bed while not fully awake and do things that you may not remember, such as sleep-walking or sleep-eating. If this happens, your healthcare provider will probably recommend that you stop taking Intermezzo.
- Intermezzo can cause severe allergic reactions. If you have an allergic reaction to this medication, you should never take it again.
- This sleep medicine should be used with caution in people with sleep apnea or other breathing problems, as it could make these problems worse.
- This drug has been reported to cause or worsen depression. Let your healthcare provider know if you think you may be depressed or if your depression is becoming worse.
- Liver disease may affect the way your body handles this product. You may need a lower Intermezzo dosage.
- Intermezzo may react with several other medications (see Intermezzo Drug Interactions).
- Intermezzo is a pregnancy Category C medication. This means that it may not be safe for use during pregnancy, although the full risks are currently unknown (see Intermezzo and Pregnancy).
- Intermezzo passes through breast milk. Therefore, if you are breastfeeding or plan to start, discuss this with your healthcare provider prior to taking the drug (see Intermezzo and Breastfeeding).