Intermezzo Side Effects

During extensive clinical research, the most commonly reported side effects of Intermezzo included headaches, fatigue, and nausea. In most cases, however, reactions to this sleep medicine were minor and easy to treat. However, you should contact your healthcare provider right away if you experience hallucinations, suicidal thoughts, or an unexplained rash.

An Introduction to Intermezzo Side Effects

Just like any medicine, Intermezzo® (zolpidem sublingual tablet) can cause side effects. However, not everyone who takes the medication will have problems. In fact, most people tolerate it quite well. If side effects do occur, in most cases, they are minor and either require no treatment or are treated easily by you or your healthcare provider. In a survey of hospitalized people, less than 1 percent of those who took normal doses of Intermezzo reported experiencing side effects.
(This article covers many, but not all, of the possible side effects with Intermezzo. Your healthcare provider can discuss a more complete list with you.)

Common Side Effects of Intermezzo

Intermezzo has been studied extensively in clinical trials. In these studies, the side effects that occurred in a group of people taking Intermezzo were documented and compared to the side effects that occurred in a similar group of people taking a placebo (a tablet that does not contain any active ingredients).
In these studies, the most common bothersome, but not usually dangerous, side effects of Intermezzo included:
  • Headaches -- in up to 3 percent of people
  • Fatigue (presumably next-day fatigue, although this is not specified) -- up to 1 percent
  • Nausea -- up to 1 percent.
It should be noted that 1 percent of people taking the placebo also reported nausea, so this is probably not a true side effect.

Intermezzo Medication Information

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